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eCAM Advance Access published online on May 8, 2006
eCAM, doi:10.1093/ecam/nel022
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© The Author (2006). Published by Oxford University Press. All rights reserved.
Received September 13, 2005
Accepted March 23, 2006

Review

Maggot Therapy: The Science and Implication for CAM Part II--Maggots Combat Infection

Yamni Nigam 1 *, Alyson Bexfield 2, Stephen Thomas 3, and Norman Arthur Ratcliffe 4

1 School of Health Science, University of Wales Swansea, Singleton Park, Swansea SA2 8PP, UK
2 School of Health Science, University of Wales Swansea, Singleton Park, Swansea SA2 8PP, UK; Department of Biological Sciences, University of Wales Swansea, Singleton Park, Swansea SA2 8PP, UK
3 Biosurgical Research Unit (SMTL), Princess of Wales Hospital, Coity Road, Bridgend CF31 1RQ, UK
4 Department of Biological Sciences, University of Wales Swansea, Singleton Park, Swansea SA2 8PP, UK

* To whom correspondence should be addressed.
Yamni Nigam, E-mail: Y.Nigam{at}swansea.ac.uk


  Abstract

Maggot therapy employs the use of freshly emerged, sterile larvae of the common green-bottle fly, Phaenicia (Lucilia) sericata, and is a form of artificially induced myiasis in a controlled clinical situation. Maggot therapy has the following three core beneficial effects on a wound: debridement, disinfection and enhanced healing. In part II of this review article, we discuss clinical infections and the evidence supporting the potent antibacterial action of maggot secretions. Enhancement of wound healing by maggots is discussed along with the future of this highly successful, often controversial, alternative treatment.

Keywords: Maggot debridement therapy; MRSA; antimicrobial; Lucilia sericata; wounds.
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