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eCAM 2004 1(1):49-62; doi:10.1093/ecam/neh015
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© Oxford University Press, 2004.


Review

An Alternative Approach to Atopic Dermatitis: Part I—Case-Series Presentation

Hiromi Kobayashi1,*, Kuniaki Takahashi2, Nobuyuki Mizuno1, Haruo Kutsuna1 and Masamitsu Ishii1

1Department of Dermatology, Osaka City University Graduate School of Medicine, Osaka, Japan, and 2Takahashi Dermatology Clinic, Daito City, Osaka, Japan

Atopic dermatitis (AD) is a complex disease of obscure pathogenesis. A substantial portion of AD patients treated with conventional therapy become intractable after several cycles of recurrence. Over the last 20 years we have developed an alternative approach to treat many of these patients by diet and Kampo herbal medicine. However, as our approach is highly individualized and the Kampo formulae sometimes complicated, it is not easy to provide evidence to establish usefulness of this approach. In this Review, to demonstrate the effectiveness of the method of individualized Kampo therapy, results are presented for a series of patients who had failed with conventional therapy but were treated afterwards in our institution. Based on these data, we contend that there exist a definite subgroup of AD patients in whom conventional therapy fails, but the ‘Diet and Kampo’ approach succeeds, to heal. Therefore, this approach should be considered seriously as a second-line treatment for AD patients. In the Discussion, we review the evidential status of the current conventional strategies for AD treatment in general, and then specifically discuss the possibility of integrating Kampo regimens into it, taking our case-series presented here as evidential basis. We emphasize that Kampo therapy for AD is more ‘art’ than technology, for which expertise is an essential pre-requisite.

Keywords: Kampo medicine – atopic dermatitis – eczema – diet – herbal medicine – herbal therapy


*For reprints and all correspondence: Hiromi Kobayashi, Department of Dermatology, Osaka City University Graduate School of Medicine, 1–4–3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan. E-mail: hiromik{at}med.osaka-cu.ac.jp


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