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eCAM Advance Access originally published online on May 8, 2006
eCAM 2006 3(3):303-308; doi:10.1093/ecam/nel022
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© 2006 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commerical use, distribution, and reproduction in any medium, provided the original work is properly cited.

Review

Maggot Therapy: The Science and Implication for CAM Part II—Maggots Combat Infection

Yamni Nigam1, Alyson Bexfield1,2, Stephen Thomas3 and Norman Arthur Ratcliffe2

1 School of Health Science, University of Wales Swansea Singleton Park, Swansea SA2 8PP, UK, 2 Department of Biological Sciences, University of Wales Swansea Singleton Park, Swansea SA2 8PP, UK, and 3 Biosurgical Research Unit (SMTL), Princess of Wales Hospital Coity Road, Bridgend CF31 1RQ, UK

Maggot therapy employs the use of freshly emerged, sterile larvae of the common green-bottle fly, Phaenicia (Lucilia) sericata, and is a form of artificially induced myiasis in a controlled clinical situation. Maggot therapy has the following three core beneficial effects on a wound: debridement, disinfection and enhanced healing. In part II of this review article, we discuss clinical infections and the evidence supporting the potent antibacterial action of maggot secretions. Enhancement of wound healing by maggots is discussed along with the future of this highly successful, often controversial, alternative treatment.

Keywords: maggot debridement therapy – MRSA – antimicrobial – Lucilia sericata – wounds

For reprints and all correspondence: Yamni Nigam, University of Wales Swansea, Singleton Park, Swansea SA2 8PP, UK. E-mail: Y.Nigam{at}swansea.ac.uk


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